With nine games remaining, Graham Potter’s side are battling to avoid relegation having failed to win a single game since the turn of the year.
However, they will be boosted by having an almost full-strength squad at their disposal, with impressive Argentine Alexis Mac Allister and former Chelsea full-back Tariq Lamptey now bedded in at the club.
For Arsenal, the scars are still fresh from their disastrous defeat against Manchester City at the Etihad. Mikel Arteta’s side are rapidly losing hope of securing a Europa League place, while problems continue to mount after injuries to Pablo Mari and Granit Xhaka.
Here is everything you need to know:
When is it and what time is kick-off?
The match will start at 3pm on Saturday 20 June at the Amex Stadium.
How can I watch it online and on TV?
The match is being broadcast live on BT Sport.
What is the team news?
Exciting Argentinian Alexis Mac Allister will be available for selection with only Jose Izquierdo missing through injury.
Lucas Torreira and Kieran Tierney are both available for Arsenal after a period on the sidelines.
What are the predicted line-ups?
Brighton: Ryan, Montoya, Duffy, Dunk, Bernardo, Stephens, Propper, Trossard, Mooy, Gross, Maupay.
Arsenal: Leno, Bellerin, Holding, Mustafi, Tierney, Guendouzi, Torreira, Ceballos, Saka, Nketiah, Aubameyang.
What are the odds?
Brighton – 12/5
Draw – 19/10
Arsenal – 11/8